红桂心力康冲剂治疗慢性收缩性心力衰竭的临床研究

Honggui Xinlikang:Clinical Research on Its Treatment of Chronic Systolic Heart Failure

目的:观察红桂心力康冲剂治疗慢性收缩性心力衰竭的临床疗效。方法:178例心肾阳虚、水泛血瘀型慢性收缩性心力衰竭患者按随机原则分为两组,治疗组106例口服中药红桂心力康冲剂,15g/次,3次/日,病情重者,配合小剂量的西药对症治疗,对照组72例给予常规西药治疗。两组均以7日为1个疗程,治疗4个疗程后观察疗效并作统计学分析。结果:治疗组显效率(43.39%)和总有效率(91.51%)显著高于对照组(26.39%和80.56%,P<0.01和P<0.05),临床应用未发现毒副作用和不良反应。结论:红桂心力康冲剂具有温阳益气,活血利水功效。在改善心功能,纠正心律失常方面均优于常规治疗对照组,对心动过缓或过速的心力衰竭患者均可应用。

Objective ：To observe the therapeutic effect of Honggui xinlikang in thetreatment of chronic systolic heart failure. Methods ：178 cases with chronic systolic heart failure were randomly divided into 2 groups, the treatment group （106 cases, were treated by Honggui xinlikang , as well as routine western medicine） and the control group （72cases, were merely treated by routine western medicine）. Results：The obvious effective rate of treatment group（43.39% ） is sig nificantly higher than that in control group （26. 39% ） （ P 〈 0. 01 ）, and the total effective rate of treatment group （91.51% ） is significantly higher than that in control group（ 80.56% ） （P 〈 0.05 ）. Conclusion：Honggui xinlikang granule has the efficaey of supplementing Qi and nourishing Yang,promoting blood circulation and diuresis. It＇s better thun conventional therapy in improving cardiac function and correcting arrhythmia. It could be used to treat heart failure patients with bradyeardia or taehycardia.