摘要
手性稀土配合物催化的亚膦酸酯对醛的不对称加成(Pudovik)反应研究钱长涛黄太生(中国科学院上海有机化学研究所金属有机化学开放实验室上海200032)关键词对映选择性加成Pudovik反应手性镧配合物α-羟基膦酸酯分类号O643.32光学纯的α-羟...
La Li 6,6′ diphenyl binaphthol complex, prepared in situ from ( S ) dilithium 6,6′ diphenyl binaphthooxide, lanthanum trichloride, sodium hydroxide and water at room temperature in tetrahydrofuran, could effectively catalyzed the reaction of dialkyl phosphite with aldehydes to give α hydroxy phosphonates in high yields with modest enantioselectivity (39%-74% e.e.). Further studies on the asymmetric reaction is now in progress.
出处
《分子催化》
EI
CAS
CSCD
北大核心
1997年第6期455-457,共3页
Journal of Molecular Catalysis(China)
关键词
手性
镧配合物
羟基膦酸酯
不对称加成
Enantioselective addition, Pudovik reaction, Chiral La complex, α Hydroxy phosphonate