头颅CT所见脑萎缩与年龄关系的相关分析

Analysis of the relationship between brain atrophy and age by skull CT

目的探讨脑萎缩患病率与年龄的关系，寻找脑萎缩与发病年龄的规律，为防治脑萎缩提供临床依据。方法对我院15--92岁的4272例头颅CT进行分析，其中2727例做了脑室、脑沟和脑池的测定。按5岁一个年龄组进行分组。结果2727例中经头颅CT提示脑萎缩897例，各年龄组都可以发生脑萎缩。35～39岁以上年龄组，随年龄增加患病率逐渐增加。中青年期（15--44岁）、老年前期（45～49岁）和老年期（60--92岁）脑萎缩患病率分别为4．6％、27．3％和81．5％，3组患病率有显著差异（P〈0．05），男性正常出现率明显低于女性，而脑萎缩的患病率明显高于女性（χ^2=2854．1，P〈0．05）。结论脑萎缩的发生与年龄有相关性，老年人脑萎缩的发病率高。45--49岁组至75～79岁组男、女间脑萎缩患病率存在差异。

Objective To study the relationship between brain atrophy and age, and to explore the regulation of brain atrophy and age. Methods Total 4272 cases of skull CT of 15--92 years old patients in our hospital were analyzed. The measurement of cerebral ventricle, cortical sulci and cistern in 2727 cases had been taken. They were divided into several groups according to the age of 5. Results Some 897 of 2727 patients had brain atrophy ,each age can get the possibility of brain atrophy. Over 35--39 years old group fell into brain atrophy increasingly. The rate of brain atrophy of the medium adolescence （15--44 years old）, presenium （45--48 years old） , senectitude（60--92 years old） were 4. 6%, 27.3% and 81.5% respectively. There were differences among these samples（P〈0.05）, male were higher than female obviously（χ^2=2854.1, P〈0.05）. Conclusion The rate of brain atrophy has positive correlation with age, the incidence rate of brain atrophy is high in the elderly. The prevalence rates of brain atrophy between male and female from 45--49 years old group to 75--79 years old group have statistical differences.