贝那普利与卡维地洛联合应用治疗充血性心力衰竭

Application of Combination Therapy of Benazepril and Carvedilol in Treatment of Congestive Heart Failure

目的:观察血管紧张素转换酶抑制剂(ACEI)贝那普利和非选择性β-受体阻滞剂卡维地洛联合应用治疗慢性充血性心力衰竭(CHF)患者的临床疗效。方法:利用贝那普利和卡维地洛联合治疗CHF患者36例,并与单用贝那普利治疗CHF患者32例进行疗效比较。结果:治疗组与对照组有效率分别为94.4%和68.8%(P<0.05),两组有显著性差异。结论:贝那普利和非选择性β-受体阻滞剂卡维地洛联合应用是治疗慢性充血性心力衰竭安全有效的方法。

Objective.. To observe the clinical efficacy of angiotensin-converting enzyme inhibitor （ACEI） Benazepril combined with non-selective β-blocker Carvedilol in the treatment of chronic congestive heart failure （CHF） patients. Methods：36 patients of CHF （treatment group） were treated with combination therapy of Benazepril and Carvedilol were compared with 32 cases （control group） treated with single Benazepril in the clinical efficacy. Results：The total efficiency of the treatment group and the control group were 94. 4% and 68. 8%, respectively （P〈0.05）. Conclusion. The combination of Benazepril and non-selective β-β-ocker Carvedilol is a safe and effective therapy for chronic congestive heart failure.