宫颈锥切术对宫颈上皮内瘤变Ⅱ～Ⅲ级的诊治价值

The value of diagnosis and treatment of conization of cervix to cervical intraepithelial neoplasia Ⅱ～Ⅲ grade

目的探讨宫颈锥切术对宫颈上皮内瘤变（CIN）Ⅱ～Ⅲ级的诊断及治疗价值。方法经阴道镜下宫颈活检诊断为CIN Ⅱ～Ⅲ级并行宫颈锥切术的患者76例，对比宫颈锥切术前后病理组织学结果及治疗方法等临床资料，进行回顾性分析。结果病理组织学诊断符合率为48．68％，升级24例（31．58％），其中浸润癌8例（10．53％）；降级15例（19．74％）。结论CIN Ⅱ～Ⅲ级行诊断陛宫颈锥切术，可以提高诊断准确率，预防浸润癌的漏诊，同时又是一种重要的治疗性手术。

Objective To explore the value of diagnosis and treatment of conization of cervix to cervical intraepithelial neoplasia （CIN） Ⅱ～Ⅲ grade. Methods The data of 76 patients diagnosed as CIN Ⅱ～Ⅲ grade through pre-operative multiple -punch biopsies from July 1st 2006 to June 30th 2007 was retrospectively analyzed. Compared the pathohistology and treatment methods before and after conization of cervix. Results Accordance rate of diagnosis in pre-operative cervical biopsies under vaginoscopy was 48.68%, pathological up-grade were 24 cases （31.58%）, among invasive carcinomas were 8 cases （10.53%）, pathological down-grade were 15 cases （ 19.74% ）. Conclusion Diagnostic cervical conization could enhance the rate of diagnosis, and prevent the omission of invasive carcinomas for the patients with CIN Ⅱ～Ⅲ grade.