肺心病急发期中医证型与上呼吸道菌群及免疫相关性研究

Upper Respiratory Tract Flora and Pulmonary Heart Disease Syndrome of TCM in Acute Stage:immune relationship

目的:通过对慢性肺心病急发期患者两种常见中医证型上呼吸道菌群及免疫的研究,探讨中医辨证分型与上呼吸道菌群及免疫的相关性。方法:对51例慢性肺心病急发期痰热壅肺型、痰瘀阻肺型患者,进行上呼吸道菌群及免疫功能指标检测并进行分析。结果:慢性肺心病急发期患者两证型均有上呼吸道菌群失调和免疫功能的低下,两型对比有显著差异。结论:人体上呼吸道菌群和免疫功能指标,可作为研究慢性肺心病急发期发病机理及中医辨证分型的依据之一。上呼吸道菌群失调和免疫功能低下是慢性肺心病急发期中医辨证分型的病理基础。

Objective： To observe chronic pulmonary heart disease in acute stage on the relations between upper respiratory tract flora and immune function and syndrome of TCM, It applied the ory foundation for clinical diagnosis ,prevention and cure of the respiratory tract disease, Methods： Choosing 51 cases that was the the stage of acute attack of chronic bronchus to partitionsyn drome by differential diagnosis, And did some contrasts between the partition syndrome by differential diagnosis about the stage of acute attack of chronic bronchus and functions examine about Microecology and Immune in the respiratory tract, Results ：The acute stage of chronic bronchus and the partition syndrome by differential diagnosis had typical maladjustment of microecology and low immunefunction, Conclusion： The results suggest that the indices of microecology and immune function of body could be a foundation that researching the morbidity mechanism of chronic bronchus and the partition syndrome by differential diagnosis. It suggested that their pathologic foundation were maladjustment of microecology and low immune function when the respiratory tract was infected.