添加壳聚糖的藻酸盐印模材料抗菌性能研究

Antibacterial Activity of Dental Alginate Impression Materials Impregnated with Chitosan

目的:对添加壳聚糖的藻酸盐印模材料的抗菌性进行测试,为口腔抗菌印模材的研究奠定基础。方法:分别以不同的添加比将不同分子量和脱乙酰度的壳聚糖加入藻酸盐印模材料中,采用薄膜密着法分别测试添加抗菌成分后印模材料对大肠杆菌,金黄色葡萄球菌的抗菌活性。结果:壳聚糖分别以1%和1.4%的添加比添加到藻酸盐印模材料中,对大肠杆菌和金黄色葡萄球菌有最好的抗菌性。随着脱乙酰度的提高,抑菌率均可达到100%。结论:添加壳聚糖的藻酸盐印模材料具有良好的抗菌效果。

Objective：To measure the antibacterial activity of the alginate impression materials impregnated with chitosan.Methods：Chitosan of different molecular weight and deacetyl degree were added into dental alginate impression materials with different ratios.Their antibacterial activities for Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC6538 were tested according to the Chinese and Japanese standards.Results：The alginate impression materials impregnated with Chitosan in the ratios of 1% and 1.4% has the best antimicrobial ability for Escherichia coli and Staphylococcus aureus respectively.The bacteriostasic rate could reached 100% with the increasing of deacetyl degree.Conclusions：The alginate impression materials impregnated with chitosan has excellent antimicrobial ability.