灵芝孢子油免疫调节作用的研究

Study on the immunoregulatory function of ganoderma iucidum spores oil

目的:研究灵芝孢子油对小鼠免疫功能的调节作用。方法:分别以183、367、1100 mg/kg b.wt.剂量的灵芝孢子油对小鼠连续灌胃30 d后,测定各项免疫指标。结果:灵芝孢子油能促进小鼠的脾淋巴细胞增殖转化作用及小鼠的迟发性变态反应,提高小鼠的抗体生成细胞和血清溶血素水平,增强小鼠巨噬细胞吞噬能力。结论:灵芝孢子油具有增强小鼠免疫功能的作用。

Objective： To study the immunoregulation effect of Oanoderma lucidum spores oil on mice. Methods： After administration of Ganoderma lucidum spores oil for 30 days conseutively with the dose of 183, 367 and 1 100 mg/kg BW, immunological indexes were measured. Results： Proliferation and transformation of spleen lymphocytes in the mice were increased, delayed anaphylaetie reaction was intensified, the number of antibody-Producing cells and the level of serum hemolysin and the phagocytosis of macrophage in abdominal cavity were also raised. Conclusion： Oanoderma lueidum spores oil can strengthen the immunofunction of mice.