甘草多糖免疫调节作用的研究

Immune-modulation of Glycyrrhiza Polysaccharide

目的:研究甘草多糖对小鼠免疫系统功能的影响。方法:以体内给药方式,对实验动物进行碳粒廓清实验、淋巴细胞增殖实验、血清溶血素水平测定实验,研究甘草多糖对非特异性和特异性免疫系统的影响。结果:实验表明,与空白对照组进行比较,低、中、高剂量多糖给药组小鼠的免疫能力均有显著性提高(P<0.05),并呈现一定剂量依赖关系,且达到阳性对照药物组水平。结论:甘草多糖对正常小鼠的免疫能力有促进作用。

Objective： To study the effect of Glycyrrhiza Polysaccharide to the immunity function of mice. Method： Glycyrrhiza Polysaccharides were given （ig） to mice for experiment in different doses. After two weeks, carbon expurgation, lymphopoiesis and blood serum hermolysin were carried out on the mice. Results： The results showed that different doses of Glycyrrhiza Polysaccharide could promote the immunity activity of mice obviously and the effect depended on the dose. Conclusion： Glycyrrhiza Polysaccharides can improve advance the immunity of healthy mice.