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PTEN及其与肺癌关系的研究进展 被引量:2

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作者 刘月娥 姜达
出处 《实用癌症杂志》 2008年第5期543-545,共3页 The Practical Journal of Cancer
关键词 PTEN基因 肺癌
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参考文献29

  • 1Li J,Yen C ,Liaw D,et al. PTEN ,a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer [ J]. Science, 1997,275 (5380) : 1943.
  • 2Steck PA,Pershouse MA, Jasser SA, et al. Identification of a candidated tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers [ J ]. Nat Genet, 1997,15 (4) : 356.
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二级参考文献52

  • 1FRANCISCA V,SHIVAPRIYA R,NORIAKI N,et al.Phosphorylation of the PTEN tail regulates protein stability and function[J].Mol Cell Biol,2000,20(14):5010-5018.
  • 2BANDYOPADHYAY S,SUDHA K,HIROTA S,et al.PTEN up-regulates the tumor metastasis suppressor gene Drg1 in prostate and breast cancer[J].Cancer Res,2004,64(11):7655-7660.
  • 3GRAFFENRIED L,FULCHER L,FRIEDRICHS W,et al.Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway[J].Ann Oncol,2004,15(10):1510-1516.
  • 4KANDASAMY K,SRIVASTAVA R.Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor nec rosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells[J].Cancer Res,2002,62(9):4929-4937.
  • 5SORIA J,LEE H,LEE J,et al.Lack of PTEN expression in non-small cell lung cancer could be related to promotor methyl ation[J].Clin Cancer Res,2002,8(5):1178-1184.
  • 6BEPLER G,SHARMA S,CANTOR A,et al.RRM1 and PTEN as prognostic parameters for overall and disease-free survival in patients with non-small cell lung cancer[J].J Clin Oncol,2004,22(10):1878-1885.
  • 7Wu Y.PTEN 2 a golgi2 associated testis specific homologue of the PTEN tumor suppressor lipid phosphatase[J].J Biol Chem,2001 ;276(24):21745
  • 8Dong XY.Identification of two novel CT antigens and their capacity to elicit antibody response in hepatocellular carcinoma patients[J].Br J Cancer,2003;89(2):291
  • 9Parsons R.Human cancer,PTEN and the PI23K kinase pathway[J].Semin Cell Dev Biol,2004; 15(2):171-176
  • 10Sulis ML,Parsons R.From pathology to biology[J].Trends in Cell Biology,2003; 13(9):478-483

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