超临界CO_2提取当归油及其化学成分分析

The Extraction of Chemical Constituents from Angelica sinensis with Supercritical CO_2 Fluid and the Constituents Analysis

目的分析活血止痛胶囊中超临界提取的当归油成分。方法采用气相色谱-质谱法(GC-MS)分析超临界提取的当归油化学成分。结果共测定65种化学成分,鉴定62种,其中藁苯内酯含量为74.4%。结论该工艺对当归有效成分具有较高的提取率,较好的保留了药效成分。

Objective To analyse the chemical constituents of Angelica sinensis extracted from Huoxue Zhitong Capsules with supercritical CO2 fluid. Methods The Angelica sinensis were extracted with supercritical CO2 fluid. The GC-MS was used to analysis. Results Sixty-five components were separated, Sixty-two components were identified and ligustilide accounted for 74.4 %. Conclusion The optimal process is feasible with the advantages of high production and active ingredient.