我国国家自然科学基金资助眼科学研究项目的现状分析

Analysis of ophthalmic projects granted by National Natural Science Foundation

目的根据我国眼科研究项目获得国家自然科学基金资助情况探讨我国眼科学基础研究现状。方法对1986至2007年共22年我国国家自然科学基金资助眼科学研究项目的资助情况、研究队伍、研究领域和基金项目完成情况等进行回顾性统计及分析。结果22年内眼科学领域共有来自47个依托单位的228人获得了国家自然科学基金资助，立项数为323项，资助总经费约为6674万元。视网膜疾病、角膜疾病、青光眼、视神经疾病、近视眼、白内障等6种眼病的相关研究为申请项目和资助项目的主要涉及领域，约70％项目属于应用基础研究。至2006年底前已结题项目为165项，在国内期刊发表论文610余篇，在科学引文索引收录期刊发表论文140余篇，培养人才600余名，获得各类成果20余项。结论国家自然科学基金资助眼科学的研究项目和成果数量逐年增加；研究领域和主要研究单位相对集中；在肯定国家自然科学基金资助对我国眼科学基础研究和人才培养发挥了重要作用的同时，强调应进一步加强临床研究、连续性深入研究、临床转化研究及多学科交叉研究。

Objective To understand the status of basic research work in the field of ophthalmology by analyzing the projects funded by the National Natural Science Foundation of China （NSFC） from the year of 1986 to 2007, and offer as a reference to the ophthalmologists and researchers. Methods NSFC supported ophthalmology projects in the 22 year＇s period were collected from the database of NSFC. The field of funded projects, the research team and their achievements were analyzed. Results There were 228 applicants from 47 home institutions were funded in the field of ophthalmology during the past 22 years, 323 projects funded with 66. 74 million Yuan in total, in which 165 projects were fulfilled before the end of 2006. The applied and funded projects mainly focus on six different kinds of research area related to retinal diseases, corneal diseases, glaucoma, optic nerve diseases, myopia and cataract, and 70% of them were basic research in nature. As a brief achievement of 165 fulfilled projects, more than 610 papers were published in domestic journals, over 140 papers were published in Science Citation Index journals, more than 600 people were trained, and over 20 scientific awards were obtained. Conclusion The number of funded projects and achievement of fulfilled projects in the discipline of ophthalmology gradually increased over the past two decades, the research fields were concentrated in certain diseases. NSFC has played an important role in promoting the development of ophthalmology research and bringing up specialists in China. However, clinical research, continuously research, transforming from basic research to clinic applications and multidisciplinary cross studies should be strengthened. （Chin J Ophthalmol,2008,44：839- 844）