期刊文献+

抗抑郁药帕罗西汀的合成研究进展 被引量:5

Progress in Synthesis of Antidepressant(-)-Paroxetine
下载PDF
导出
摘要 本文综述了抗抑郁药帕罗西汀及其中间体的合成研究进展. This article reviewed the progress in the synthesis of antidepressant paroxetine and its key intermediates.
出处 《化学研究》 CAS 2008年第3期102-107,共6页 Chemical Research
基金 重庆市自然科学基金资助项目(CSTC 2007BB5369) 人事部回国人员重点项目(2002-99)
关键词 帕罗西汀 抗抑郁药 合成 paroxetine antidepressant drug synthesis
  • 相关文献

参考文献20

  • 1Joseph A R, Gary R M, Jane T H, et al. Effect of paroxetine hydrochloride(Paxil) on fatigue and depression in breastcancer patients receiving chemotherapy[J]. Breast Cancer Res Treat, 2005, 89:243 -249.
  • 2Cunningham V, Constable J, CHannah R. Environmental risk assessment of paroxetine[ J ]. Environ Sci Technol, 2004, 38:3351 - 3359.
  • 3Pastre J C, Correia C R D. Efficient Heck arylations of cyclic and acyclic acrylate derivatives using arenediazonium tetrafluoroboratesL A new synthesis of the antidepressant drug (±)-paroxetine[ J]. Org Lett, 2006, 8(8) :1557 -1660.
  • 4Cossy J, Mirguet 0, Pardo D G, et al. Diastereoselective conjugate addition of organocuprates to chiral racemic olefinic amido esters. Formal total synthesis of paroxetine[ J]. New J Chem, 2003, 27:475 -482.
  • 5Cossy J, Mirguet O, Pardo D G, et al. A short formal synthesis of paroxetine. Diastereoselective cuprate addition to a chiral racemic olefinic amido ester[ J]. Tetrahedron Lett, 2001, 42:7805 - 7807.
  • 6Yu M S, Lantos I, Peng Z Q, et al. Asymmetric synthesis of (-)-paroxetine using PLE hydrolysis[J]. Tetrahedron Lett, 2000, 41:5647 - 5651.
  • 7Liu L T, Hong P C, Huang H L, et al. Asymmetric syntheses of trans-3,4-disubstituted 2-piperidinonesand pipefidines[ J]. Tetrahedron :Asymmetry, 2001, 12:419 - 426.
  • 8Chen C Y, Chang B R, Tsai M R, et aI. Regioselective reduction of N-alkyl-3-sulfonyl glutarimides to δ-1actams. Formal synthesis of (+) -paroxetine and (+) -tacamonine[ J]. Tetrahedron, 2003, 59:9383 - 9387.
  • 9Niddam V. Process for purifying paroxetine intermediate of alkoxy-derivative-free and process for preparing alkoxy-derivative-free paroxetine[ P]. EL 594611807, 2001 - 06 - 13.
  • 10Hughes G, Kimura M, Buchwald S 1,. Catalytic enantioselective conjugate reduction of lactonesand and lactams[ J]. J Ant Chem Soc, 2003, 125:11253 - 11258.

同被引文献68

引证文献5

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部