北京市海淀区2006年临床诊断与实验室确诊细菌性痢疾流行特征分析

ANALYSIS OF EPIDEMIC CHARACTERISTICS OF CLINICAL AND LABORATORY DIAGNOSED FOR CACILLARY DYSENTERY CASES IN HAIDIAN DISTRICT IN 2006

[目的]对海淀区2006年128例临床细菌性痢疾个案进行调查,分析实验室确诊菌痢、其他致病菌所占比例,以及流行病学特征,为2008年奥运会提供菌痢本底资料,有针对性地提出防控策略。[方法]临床诊断菌痢个案调查,进行流行病学综合分析。菌痢检测应用国标GB16002-1995标准进行细菌培养鉴定。[结果]检出致病菌33株,检出率25.78%,志贺氏菌属16株占12.50%,致腹泻性大肠埃希氏菌8株占6.25%,副溶血性弧菌4株占3.13%,变形杆菌5株占3.19%,未检出致病菌占74.22%。实验室确诊菌痢男女之比0.45︰1,以20岁组确诊菌痢为最高,职业以干部职员、学生为最多,单位以学校、企业、公司为主。[结论]志贺氏菌检出率仅为12.50%,其他致病菌检出率为13.28。确诊菌痢男女之比0.45︰1与临床菌痢男女之比1.24︰1反差很大。干部职员、学生发病较高,应加强重点人群防治工作。

[Objective] To investigate the clinical bacillary dysentery of 128 patients in Haidian District. and to analyze the proportions of dysentery bacterium and other nosogenetic bacterias diagnosed by laboratory as well as epidemic characteristics, so as to provide basic and reliable data for 2008 Olympics of Beijing and draw off pertinent measures on prevention and control of bacillary dysentery. [ Methods ] Epidemiologic synthetically analysis were performed to analyze the data of the bacillary dysentery cases. The isolate bacteria from clinical specimen were identified according to the GB16002-1995. [Results] 33 nosogenetie Strains are isolated and the detective rate was 25.7%. 16 S.dysenteriae were tested with the proportion of 12.50%; 8 Enteropathogenic E.coli were tested accounted for 6.25% ; 4 V.parahemolyticus were tested accounted for 3.13% ; 5 Proteus were tested with the proportion of 3.19%. The sexual ratio of laboratorial diagnosed bacillary dysentery is 0.45 ： 1 （male： female）. The age group at the age of 20 to 29 had the highest incident rate; the main professions were office clerks and students, and enterprise, company and school had higher incident rate. [ Conclusion ] The detective rate of S.dysenteriae was 12.50% and other nosogenetic bacterias was 13.28%. The sexual ratios of bacillary dysentery are different between laboratorial diagnosed （0.45 ： 1 ） and clinical diagnosed cases （ 1.24 ： 1 ）. The prevention and cure of bacillary dysentery need to be strengthened in office clerks and students, who have the higher incident rate.