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动态浊度法检测C群脑膜炎球菌多糖原液细菌内毒素含量

A kinetic turbidimetric assay forquantitatively detecting the bacterial endotoxin content of group C meningococcal polysaccharide bulks
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摘要 采用动态浊度法对多批C群脑膜炎球菌多糖原液进行细菌内毒素含量检测,同时设供试品干扰试验,并与凝胶限量法进行对比分析。从而建立了C群脑膜炎球菌多糖原液细菌内毒素定量检测方法和质量控制指标。 A kinetic turbidimetric assay was compared with the gel-clot technique for quantitatively detecting the bacterial endotoxin content of different group C meningococcal polysaccharide bulks, in this way a quantitative assay for detecting the bacterial endotoxin content of group C meningococcal polysaccharide bulks was established.
出处 《微生物学免疫学进展》 2008年第3期15-20,共6页 Progress In Microbiology and Immunology
关键词 C群脑膜炎球菌多糖原液 细菌内毒素含量检测 凝胶限量法 干扰试验 Group C meningococcal polysaccharide bulk Bacterial endotoxin test (BET) Gel-clot technique Interfering test
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参考文献3

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二级参考文献2

  • 1Thomas H,Ingeborg A,Susanne B,et al.Novel Pyrogen Tests Based on the Human Fever Reaction[OL].The European Centre for Validation of Alternative Methods (ECVAM),2003,29:99
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