期刊文献+

热敏性三嵌段聚酯-聚乙二醇共聚物的特性与应用 被引量:2

Characteristics and Application of Thermosensitive Triblock Polyesterpoly(ethylene glycol)Copolymers
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摘要 三嵌段聚酯-聚乙二醇共聚物具有热敏性、生物相容性、生物降解性、增溶性及缓释特性,是一种良好的注射用缓释制剂载体。本文综述了此类共聚物的特性及其在药物传递系统中的应用。 The triblock polyester-poly(ethylene glycol) copolymers possess the characteristics of thermal sensitivity, biocompatibility, biodegradation, solubilization and sustained-release property. They are widely studied in pharmaceutical field as matrix of injection drug delivery system. The properties and application of these kinds of copolymers are reviewed.
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2008年第9期702-707,共6页 Chinese Journal of Pharmaceuticals
关键词 三嵌段聚酯-聚乙二醇共聚物 热敏性 凝胶 综述 triblock polyester-poly (ethylene glycol) thermosensitive gel review
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参考文献34

  • 1Shenderova A, Burke TG, Schwendeman SP. Stabilization of 10-hydroxycamptothecin in poly (lactide-co-glycolide) microsphere delivery vehicles [J]. Pharm Res, 1997, 14 (10): 1406-1414.
  • 2van de Weert M, Hennink WE, Jiskoot W. Protein instability in poly (lactic-co-glycolic acid) microparticles [J]. Pharm Res, 2000, 17(10): 1159-1167.
  • 3Churchill JR, Hutchinson FG. Continuous release formulations: US, 4526938 [P]. 1985-07-02.
  • 4Churchill JR, Hutchinson FG. Biodegradable amphipathic copolymers: US, 4745160 [P]. 1988-05-17.
  • 5Jeong B, Bae YH, Lee DS, et al. Biodegradable block copolymers as injectable drug-delivery systems [J]. Nature, 1997, 388 (6645): 860-862.
  • 6Jeong B, Bae YH, Kim SW. Biodegradable thermosensitive micelles of PEG-PLGA-PEG triblock copolymers [J]. Colloids Surf B, 1999, 16(1-4): 185-193.
  • 7Matsumoto J, Nakada Y, Sakurai K, et al. Preparation of nanoparticles consisted of poly (L-lactide) -poly (ethylene glycol)-poly (L-lactide) and their evaluation in vitro [ J]. Int JPharm, 1999, 185(1):93-101.
  • 8Lee DS, Shim MS, Kim SW, et al. Novel thermoreversible gelation of biodegradable PLGA-block-PEO-block-PLGA triblock copolymers in aqueous solution [J]. Macromol Rapid Commum, 2001, 22 (8) : 587-592.
  • 9Zentner GM, Rathi R, Shih C, et al. Biodegradable block copolymers for delivery of proteins and water-insoluble drugs [J]. J Controlled Release, 2001, 72 (1-3) : 203-215.
  • 10Packhaeuser CB, Schnieders J, Oster CG, et al. In situ forming parenteral drug delivery systems: an overview [J]. Eur J Pharm Biopharm, 2004, 58 (2) : 445-455.

二级参考文献21

  • 1陈钢,侯世祥,刘军,张瑜,卢懿,李芳琼.治疗耳聋的地塞米松原位凝胶给药系统的研究[J].中国药学杂志,2006,41(9):685-688. 被引量:8
  • 2LENAERTS V, TRIQUENEAUX C, QUARTON M, et al. Temperature-dependent rheological behaviour of Pluronic F-127 aqueous solutions[J]. Int J Pharm. 1987, 39: 121-127.
  • 3CHOI H G, JUNG J H, RYU J M, et al. Development of in situgelling and mucoadhesive acetaminophe liquid suppository [J]. Int J Pharm, 1998, 165: 33-44.
  • 4EDSMAN K, CARLFORS J, PETERSSON R. Rheological evaluation of poloxamer as an in situ gel for ophthalmic use [ J ]. Eur J Pharm Sci, 1998, 6: 105-112.
  • 5WANKA G, HOFFMAN H, ULBRICHT W. Theaggregation behavior of poly- ( oxy ethylene ) -poly- ( oxypropylene ) -poly- ( oxyethylene)-block-copolymers in aqueous solution [J]. Colloid Polym Sci, 1990,268 : 101-117.
  • 6EDSMAN K, CARLFORS J, HARJU K. Rheological evaluation and ocular contact time of some carbomer gels for ophthalmic use [J]. Int J Pharm, 1996, 137: 233-241.
  • 7CABANA A, AIT-KADI A, JUHASZ J. Study of the gelation process of polyethylene oxide-polypropylene oxide-polyethylene oxide copolymer ( poloxamer 407 ) aqueous solutions[J]. J Colloid Interface Sci , 1997, 190: 307-312.
  • 8JEONG B, LEE D S, SHON J I, et al. Thermoreversible gelation of poly( ethylene oxide) biodegradable polyester block copolymers [J]. J Polym Sci Polym Chem, 1999, 37: 751-760.
  • 9YOSHIDA T, TAKAHASHI M, HATAKEYAMA T, et al. Annealing induced gelation of xanthan/water systems[J]. Polymer, 1998, 39: 1119-1122.
  • 10Sibao Chen, Robert Pieper. International Journal of Pharmaceutics, 2005, 288(2): 207-218

共引文献11

同被引文献41

  • 1黄君,裴元英.HPLC法测定帕金森病大鼠模型中鱼藤酮血浆浓度[J].中国临床药学杂志,2005,14(3):161-163. 被引量:2
  • 2吴红,张慧,范黎,王嘉宁,任波.温敏型聚(N-异丙基丙烯酰胺/丙烯酰胺)纳米凝胶的制备及其性质研究[J].解放军药学学报,2007,23(4):245-249. 被引量:7
  • 3ZENTNER G M,RATHI R,SHIH C,et al.Biodegradable block copolymers for drug delivery of proteins and water-insoluble drugs[J].Control Release,2001,72(1-3):203-215.
  • 4PACKHAEUSER C B,SCHNIEDERS J,OSTER C G,et al.In situ forming parenteral drug delivery systems:an overview[J].Eur J Pharm Biopharm,2004,58(2):445-455.
  • 5SOPPIMATH K S,AMINABHAVI T M,DAVE A M,et al.Stimulus-responsive "smart" hydrogels as novel drug delivery systems[J].Drug Dev Ind Pharm,2002,28(8):957-974.
  • 6GHAHREMANKHANI A A,DORKOOSH F,DINARVAND R.PLGA-PEG-PLGA tri-block copolymers as an in-situ gel forming system for calciton in delivery[J].Polymer Bulletin,2007,59(5):637-646.
  • 7LI N,WANG J,YANG X,et al.Novel nanogels as drug de-livery systems for poorly soluble anticancer drugs[J].Colloids Sur B:Bio-interfaces,2011,83(2):237-244.
  • 8CHEN S,SINGH J.In vitro release of levonorgestrel from phase sensitive and thermosensitive smart polymer delivery systems[J].Pharm Develop Tech,2005,10(2):319-325.
  • 9CHEN S,SINGH J.Controlled release of growth hormone from thermosensitive triblock copolymer systems:In vitro and in vivo evaluation[J].Int J Pharm,2008,352(1-2):58-65.
  • 10Singh S, Webster DC, Singh J. Thermosensitive polymers: synthesis, characterization, and delivery of proteins [J]. Int J Pharm, 2007, 341 (1-2) : 68-77.

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