妊娠晚期妇女凝血指标的临床检测意义

Clinical Detection Significance of Coagulation Index in Late Pregnancy Women

目的探讨妊娠晚期妇女血浆中的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)和纤维蛋白原含量(FIB)的临床检测意义。方法选择90例产前检查和住院待产的妊娠晚期妇女为妊娠组和90例同期进行健康检查未婚或未孕妇女为对照组,采用CA-50血凝仪检测2组的凝血4项,并进行比较。结果妊娠组PT、APTT、TT均低于对照组,差异有统计学意义(P<0.01);而FIB则高于对照组,差异有统计学意义(P<0.01)。结论产前应密切检测凝血功能,了解各项指标的变化,防止产妇弥漫性血管内凝血形成,对提高分娩安全,保护母婴健康具有重要意义。

[Objective] To study clinical significance of detecting PT, APTT,TT and FIB in plasma of late pregnancy women. [ Methods] 90 antenatal Check-up and hospital expectant women in late pregnancy were selected as labor group, 90 unmarried or non-pregnant women who conducted health examination were selected for the control group, CA-50 coagulation Analyzer was used to determine 4 coagulation factors, and the results were compared. [ Results ] PT, APTT and TT levels of labor group were lower than that of control group, the difference was significant （ P 〈 0.01 ）, FIB level of labor group was higher than the control group, the difference was significant （ P 〈 0.01 ） . [ Conclusion ] Antenatal examination of coagulation function and understanding of the change of various indicators was of high value in disseminated intravascular coagulation prevention, delivery security enhancement and maternal and child health protection.