孟鲁司特治疗及预防小儿咳嗽变异性哮喘分析

Effect observation on montelukast in treating and preventing cough variant asthma in children

目的观察孟鲁司特治疗及预防小儿咳嗽变异性哮喘的临床疗效。方法将71例咳嗽变异性哮喘患儿随机分为观察组36例和对照组35例,对照组予酮替酚口服,治疗组予孟鲁司特口服,连用6个月。结果两组达到临床缓解所需时间及随访半年的复发率比较,均有显著性差异(P<0.01和P<0.05),观察组优于对照组。结论孟鲁司特治疗小儿咳嗽变异性哮喘疗效好,可降低复发率。

Objective To investigate the clinical effect of montelukast in treating and preventing children＇s cough variant asthma （CVA）. Methods Seventy-one children with CVA were randomly divided into observation group （n=36） and control group （n=35）. The control group was given orally ketotifen, and the observation group was treated with montelukast for six months. Results There were significant differences in time reaching clinically relieve and rate of recurrence that follow-up for six months, the observation group was better than control group （P〈0.01 and P〈0.05）. Conclusion Montelukast is effective in treatment of children＇ s CVA, and it can reduce the rate of recurrence.