摘要
目的探讨上皮性卵巢癌组织中MMP2蛋白的表达情况。方法应用免疫组织化学法检测78例上皮性卵巢癌组织中MMP2蛋白的表达。结果78例上皮性卵巢癌组织中MMP2蛋白阳性表达56例。MMP2蛋白的表达与上皮性卵巢癌组织学分型无关(P>0.05);与分化程度、临床分期和淋巴结转移有关(P<0.05)。结论MMP2蛋白与上皮性卵巢瘤组织的发生、发展及转移有关,可作为判断卵巢癌预后不良的指标。
Objective To investigate the expression of MMP2 protein in epithelial ovarian cancer tissue. Methods The expression of MMP2 protein in 78 eases of epithelial ovarian cancer tissue was detected using immunohistochemistry. Results The expression of MMP2 was detected in epithelial ovarian cancer tissue of 56 cases. The expression of MMP2 was related to differentiation degree, clinical stage, and lymph node metastasis, but not with histological type. Conclusion The expression of MMP2 protein is related to the occurrence, development and metastasis of epithelial ovarian cancer, and be used as an indicator for judging poor prognosis.
出处
《中国热带医学》
CAS
2008年第10期1694-1695,共2页
China Tropical Medicine
