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急性冠脉综合征患者BNP浓度及临床意义

The concentration of BNP and its clinical significance in patients with acute coronary aterial syndrome
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摘要 目的探讨急性冠脉综合征(ACS)患者血浆脑钠肽(BNP)浓度的变化及其临床意义。方法测定对照组49例及ACS组79例患者的血浆BNP浓度进行对比。将ACS组又分为不稳定心绞痛(UA)、非ST抬高心梗(NST-MI)、ST抬高心梗(STMI)3个亚组,对其中67例患者做冠脉照影(CAG),分为1支、2支、3支病变组,并对NSTMI组及STMI组进行心功能Killip分级,测定BNP值并比较。结果ACS组各亚组BNP浓度均高于对照组(P<0.01),STMI组BNP浓度高于UA组及NSTMI组(P<0.01)。冠脉3支、2支、1支病变组BNP浓度高于对照组(P<0.01)。NSTMI组及STMI组心功能Killip4级组、Killip3级组及Killip2级组血浆BNP浓度分别高于Killip2级组、Kil-lip1级组和对照组(P<0.01)。结论ACS组血浆BNP浓度明显升高。3支病变或心衰越重BNP浓度越高。
作者 王玉玲 买苏木 杨建中
机构地区 新疆医科大学第一附属医院
出处 《中国热带医学》 CAS 2008年第10期1742-1743,共2页 China Tropical Medicine
关键词 脑钠肽 急性冠脉综合征 KILLIP分级
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献8

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中国热带医学
2008年 第10期

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