新疆部分地区一般人群流行性感冒抗体水平监测分析

Monitoring of level of antibody to influenza virus in population in Xinjiang

目的了解新疆南、北疆两地区不同人群的流行性感冒(流感)流行状况,为预防和控制疫情提供依据。方法2006年10月在南疆地区喀什市及北疆地区伊宁市共采集一般人群血清430份,应用新疆2005～2007年度流感监测所分离病毒作为抗原,以微量半致敏血凝抑制方法进行抗体检测。结果人群对H1N1及H3N2亚型毒株的抗体阳性率明显高于B(Yamagata)及B(Victoria),其中H1N1抗体阳性率为82.79%,H3N2抗体阳性率为86.74%,B(Yamagata)为55.81%,B(Victoria)为57.91%。且H1N1、H3N2、B(Yamagata)、B(Victoria)抗体阳性率及保护率在各年龄组及地区间均有显著性差异。结论加强流感病毒抗原变异株和人群流感抗体水平的监测。

Objective To determine the distribution of antibodies to influenza virus in people of Xinjiang. Methods There 430 serum samples from general population in different residential areas （such as Yining,Kashi） of Xinjiang in October 2006 were collected and the virus isolated in in Xingjiang Regional Influenza Monitoring Institute in 2005 - 2007 was used as antigens and the antibody to influenza virus was detected with half sensitized micro - hemogglutination - inhibition test. Results The positive rates of antibodies to H1N1and H3N2 were obviously higher than B （Yamagata） and B （Victoria）. The positive rate of antibodies to H1N1 was 82.79%, the positive rate of antibodies toH3N2 was 86.74%, the positive rate of anti- bodies to B （Yamagata） was 55.81%, the positive rate of antibodies to B （Victoria） was 57.91%. The positive rate and protective rate of antibodies to H1N1, H3N2, B（Yamagata） and B （Victoria） showed significance difference between different areas and various are groups. Conclusion The monitoring of antigen variants of influenza virus and the level of human antibody to influenza virus be strengthened.