探讨骶管封闭对胶原酶溶核术后的增效作用

The synergistic action of sacral canal block with collagenase chemonucleolysis

目的:探讨骶管封闭对胶原酶溶核术后的增效作用。方法:对20例腰椎间盘突出症(其中中央型7例,单侧型9例,伴椎管狭窄2例,极外侧型1例,游离型l例)行胶原酶溶栓术后,2～7 d内再行骶管注射封闭2次。结果:术后2 wk优良率达95%,1月优良率为90%,3月后优良率为85%,6月后优良率为80%。结论:胶原酶具有特异性溶核作用,适用于单纯性椎间盘突出症,骶管封闭注射主要是镇痛消炎、改善神经的血循环,是溶核术的辅助措施,能提高溶核术的早期疗效。

Objective：To explore the synergistic action of sacral canal block with collagenase chemonucleolysis. Methods： Twenty patients with lumbar disc herniation were enrolled in the study. Seven cases had central lumbar disc herniation. Nine cases had unilateral lumbar disc herniation, and 2 out of the 9 cases had lumbar canal stenosis. One case had extremely- lateral lumbar disc herniation. And one case had free lumbar disc herniation. Sacral canal blocks were performed twice within 2 to 7 days after collagenase chemonucleolysis. Results： The excellent and good rate reached 95% at two weeks post operation. The excellent and good rate reached 90%, 85%, and 80% at 1,3 ,and 6 months post operation respectively. Conclusion： Collagenase has a specific chemonucleolysis activity. It is suitable for the treatment of simple lumbar disc herniation. Sacral canal block can enhance the early effect of collagenase chemonucleolysis as an adjuvant therapy by exerting analgesic and anti -inflammatory effects and improving nervous blood circulation.