卵巢子宫内膜异位症患者血清中可溶性细胞间粘附分子-l水平测定

Serum levels of soluble intercellular adhesion molecule 1(slCAM-1) in Ovarian endometriosis

目的:研究卵巢子宫内膜异位症患者血清中可溶性细胞间粘附分子-1(slCAM-I)的表达情况,探讨其对诊断卵巢子宫内膜异位症的价值。方法:应用双抗体夹心酶联免疫吸附试验法(ELISA)测定卵巢子宫内膜异位症患者30例及非子宫内膜异位症、正常盆腔对照组30例血清中slCAM-1水平。结果:卵巢子宫内膜异位症患者血清中slCAM-1水平明显高于正常对照组,差异有统计学意义(P<0.01)。结论:血清slCAM-1水平测定可作为辅助诊断卵巢子宫内膜异位症的免疫学指标之一。

Objective： To investigate the Serum levels of soluble intercellular adhesion molecule 1 （slCAM-1） in ovarian endometriosis, and the clinical value in diagnosis of ovarian endometriosis.Methods：The slCAM-1 levels in serum of 30 patients with ovarian endometriosis and 30 non- endometriosis,nonnal pelvic women were determined by ELISA. Results： The slCAM-1 levels in serum of patients with ovarian endometriosis were higher than those in control women （ P 〈 0. 05 ）. significance. Conclusion： The slCAM-1 may play an importan trole in the pathogenesis and progression of ovarian endometriosis. Serum sICAM-1 may be regarded as a immune index for diagnosis of ovarian endometriosis.