鲁西地区变应性鼻炎常见吸入性变应原调查分析

The survey of the common inhaled allergen in the of allergic rhinitis in the west area of Shandong

目的调查鲁西地区变应性鼻炎主要吸入性变应原,以及常见变应原的分布情况,为防治方案提供科学依据。方法采用19种标准化变应原对65例变应性鼻炎患者进行皮肤点刺试验.并将样本中18例4～18岁的患儿设为儿童组,47例19～60岁的患者设为成人组.比较两组在变应原阳性率分布上的差异。结果变应原皮肤实验阳性率前4位的变应原分别为灰尘(64.6%)、螨(61.5%)、屋尘螨(60%)、豚草花粉(41.5%),儿童组中对粉尘螨和屋尘螨的敏感程度明显高于成人组(P<0.01)。结论灰尘、螨、屋尘螨、夏秋花粉是鲁西地区最重要的变应原。

Objective To survey the main Inhaled allergens in the west area of shandong relative to allergic rhinitis and provide an instruction for prevention and immunotherapy of allergic rhinitis. Methods A total of 65 cases who were diagnosed with allergic rhinitis by history and clinical presentation, underwent a skin prick test with 19 standardized aeroaliergens ,and the important sensitizing allergens were assessed. The samples were stratified on two age groups：4-18 years（ children group, n = 18）and 19-60 years（ adults group, n = 47）. Difference of SPT responses of the 2 groups was investigated. Results The percent of patients with positive skin tests were follow：dust（ 64. 6% ） , mite （61.5 % ） , D. pteronyssinus （60%） , ragweed pollen （41.5 % ）. There ware significantly higher sensitivity to dust mite among children group compared to adults group（ P 〈 0. 01 ）. Conclusion The study shows that the dust, mite, D. pteronyssinus, flowers pollen and herbs are the most important aeroallergens in the west area of shandong.