肝母细胞瘤4例临床病理分析

Clinicopathological analysis of four cases with hepatoblastoma

目的:探讨肝母细胞瘤的临床病理特点。方法:对吉林省柳河医院病理科近30年4例肝母细胞瘤临床病理资料进行回顾性分析。结果:上皮型肝母细胞瘤2例,其中胎儿型1例,胚胎型l例;上皮间叶混合型2例。胎儿型细胞角蛋白(CK)、甲胎蛋白(AFP)阳性,波型蛋白(Vimentin)阴性;胚胎型CK阳性,AFP、Vimentin阴性;上皮间叶混合型CK、Vimentin阳性,AFP阴性。手术完整切除肿瘤4例,3例生存期超过5年。结论:肝母细胞瘤组织学类型、治疗方式与疾病的预后关系密切。

Objective To investigate the clinicopathological characteristics of hepatoblastoma. Method zed The clinicopathological da- ta from 4 cases with hepatoblastoma in Liuhe hospital of Jilin Province in recent 30 years were. Results Among 2 cases of epithelial sub- types of hepatoblastoma, there were 1 cases of fetal type, 1 of embryonal type. There were 2 cases of mixed types （ epithelial and mesenchymal components）. CK and AFP were positive and Vimentin was negative in fetal type; CK was positive and AFP and Vimentin were negative in embryonal type;CK and Vimentin were positive and AFP was negative in mixed types （epithelial and mesenchymal components）. Of 3 case with surgical resection,2 survived over 5 years. Conclusion The prognosis has close relationship with histological type and cure method of the hepatoblastoma.