摘要
目的观察糖视清(中药复方制剂)对眼内出血动物模型的止血作用和对高血糖兔眼球结膜微循环的影响并探讨其作用机制。方法用胰蛋白酶制作家兔眼内出血模型,眼底镜观察糖视清对家兔眼内出血的影响;用四氧嘧啶制作糖尿病家兔模型,用微循环观测仪观察糖视清对糖尿病家兔眼球结膜微循环的影响。结果糖视清可明显抑制胰蛋白酶所致视网膜出血;也可明显改善糖尿病家兔球结膜微循环。结论糖视清具有显著的抑制视网膜出血和改善球结膜微循环的作用。
Objective To observe the influence of Tangshiqing mistuer on the retnas of intraocular hemorrhage model and conjunetiva microcirculation of high blood sugar model in rabbits. Methods Rabbit model with intraocular hemorrhage by injecting trypsin. The effect on the intraocular hemorrhage rabbit model with Tangshiqing mistuer was observed by ophthalmoscope. Rabbit with diabetic by injecting alloxan. The effect of Tangshiqing mistuer on conjunctiva microcireulation in high blood sugar rabbits was observed by microcirculation. Results Tangshiqing mistuer can inhibit retina hemorrhage caused by trypsin and it can improve conjunetiva microcirculation of high blood sugar rabbits. Conclusion Tangshiqing mistuer have a significant function that it can inhibit retinal hemorrhage and improve conjunctival microcirculation.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2008年第5期426-429,共4页
The Chinese Journal of Clinical Pharmacology
基金
山东省中医药卫生科研计划基金资助项目(85-9210-05)
关键词
糖视清
糖尿病视网膜病变
眼内出血
球结膜微循环
Tangshiqing misture
diabetic retinopathy
intraocular hemorrhage
conjunctiva microcirculation