四种消毒剂对嗜肺军团菌杀灭效果的实验研究

STUDY ON EFFICACY OF FOUR KINDS OF CHEMICAL DISINFECTANT IN KILLING Legionella pneumophila

目的研究4种消毒剂对嗜肺军团菌杀灭效果。方法采用悬液定量杀菌试验方法,对含溴消毒剂颗粒、含氯消毒片、过氧乙酸和双链季铵盐等进行了实验室观察。结果在常温下,用含有效溴200 mg/L的消毒剂颗粒溶液、有效氯50 mg/L消毒片溶液和250 mg/L双长链季铵盐消毒液作用10 min,对悬液内嗜肺军团杆菌杀灭对数值均>5.0。用含20 mg/L过氧乙酸消毒液作用2.5 min,对悬液内嗜肺军团杆菌的杀灭对数值>5.0。4种消毒剂均随着有效浓度的增加,作用时间的延长,杀灭效果递增。结论所试验的4种消毒剂均在较低浓度下,能有效杀灭悬液内嗜肺军团菌。

Objective To study the efficacy of four chemical disinfectants in killing Legionella pneumophila. Methods Suspension quantitative germicidal test was carried out to observe the killing efficacy of bromine - containing disinfectant, chlorine - containing disinfectant, peroxyacetic acid and double -chain quaternary ammonium salt. Results The disinfectant containing 50 mg/L available bromine, that containing 200 mg/L available chlorine and 250 mg/L double - chain quaternary ammonium salt with a 10 min contact time, or peroxyacetic acid containing 20 mg/L with a 2.5 min contact time killed Legionella pneumophila by a logarithm 〉 5. 0. At ordinary temperature, the efficacy of the four disinfectants in- creased with increasing concentration and prolonging contact time. Conclusion At low concentrations, bromine - contai- ning disinfectant, chlorine - containing disinfectant, peroxyacetic acid and double - chain quaternary ammonium salt have good efficacy in killing LegioneUa pneumophila.