溶胶-凝胶生物活性玻璃超细粉体的制备与生物矿化性能研究

Preparation and Biomineralization Research of Ultrafine Sol-gel Bioactive Glass Powders

通过溶胶-凝胶和湿法研磨工艺制备了粒径分布在1μm以下的生物活性玻璃超细粉体.采用XRD、FTIR、SEM测试方法对研磨前后粉体在模拟生理溶液(SBF)中的生物矿化性能进行了对比分析与表征,结果表明:在SBF中两种粉体表面都生成了碳酸羟基磷灰石(HCA),并且经湿法研磨后的溶胶-凝胶生物活性玻璃超细粉体的生物矿化速度显著提高.通过对不同浸泡时间SBF溶液的pH值测定可知,在同样反应时间情况下,超细粉体浸泡液的pH值低于研磨前颗粒.浸泡液的ICP测试也表明研磨前后玻璃样品的离子溶出规律有所不同.

The ultrafine bioactive glass powder （uSBG） with particle size less than 1um was prepared by sol-gel and wet grinding methods. The biomineralization properties in SBF of the two powders （uSBG and SBG） were analyzed and compared by using FTIR, XRD, SEM. The results indicate that hydroxyl-carbonate apatite （HCA） forms on the surface of the two samples and biomineralization rate of uSBG is prompted significantly by wet grinding, pH value of SBF solution immersed uSBG for different times is lower than that of SBF for SBG, and ICP tests show that the releasing rules of ions are different between uSBG and SBG.