急性闭角型青光眼手术后角膜厚度的改变

Central corneal thickness changes after acute primary angle closure glaucoma treated with surgery

目的研究急性闭角型青光眼第1次发作经抗青光眼手术治疗缓解后角膜厚度是否发生改变。方法选择单眼急性闭角型青光眼第1次发作经手术治疗缓解者40例40眼，对侧未发作眼（40只）做为对照。通过手术眼压控制到正常范围2周后，以超声角膜测厚仪测量中央角膜厚度，采用配对t检验对发作眼和对侧眼的角膜厚度进行统计分析。结果就诊时患者症状持续时间1～3d者占总例数的75．00％（30／40），眼压〉60mmHg者（1mmHg=0．133kPa）占总例数的80％（32／40）。发作眼测得中央角膜厚度平均为（531．24±33．08）μm，对侧眼为（538.29±30．53）μm。发作眼较对侧跟薄，差异有统计学意义（P〈0．001）。结论急性闭角型青光眼的第1次发作经抗青光眼手术治疗后，发作眼中央角膜厚度较对侧眼薄。

Objective Investigate whether central corneal thickness changes after an episode of acute primary angle closure （APAC） attack treated with anti-glaucoma surgery. Methods A tolal of 80 eyes from 40 consecutive patients with an episode of unilateral APAC were examined. Central corneal thickness was measured with ultra-sonic pachymetry after APAC was released treated with surgery. The fellow eyes central corneal thicknesses were controis. A paired t-test was used to compare central corneal thickness between attacked and fellow eyes. Results Duration of symptoms at presentation was mainly 1 -3 day （30 of 40,75.00% ） ; Presen- ting intraocular pressure mostly 〉 60 mmHg （1 mmHg = 0. 133 kPa） （32 of 40,80.00% ）. Central corneal thickness of attacked eyes （ mean ± SD） was 531. 244 ± 33. 08μm, the fellow eyes was 538. 294± 30.531μm. The corneal thickness of attacked eyes was significantly thinner than that of the fellow eyes （P 〈 0.001 ）. Conclusions Central corneal thickness of attacked eyes was thinner than that of the fellow eyes after acute primary angle closure glaucoma treated with surgery.