α-乙酰吡啶缩氨基硫脲镍配合物及其抑菌活性研究

STUDY ON Ni(Ⅱ) COMPLEXES OF α_ACETYLPYREDINE THIOSEMICARBAZONE AND THEIR BACTERIOSTATIC ACTIVITY

合成了α＿乙酰吡啶缩氨基硫脲（ＨＬ）与镍（Ⅱ）形成的５个配合物，并通过元素分析；摩尔电导、磁矩的测定和紫外光谱、红外光谱的研究，对其进行了表征．抑菌活性实验表明：［ＮｉＬ（ＮＣＳ）］对枯草杆菌、金黄色葡萄球菌和大肠杆菌具有较强的抑制作用．

Complexes of α_acetylpyridine thiosemicarbazone with NiX 2·nH 2O(X=Cl -,NO - 3,12SO 2- 4,OAC,NCS) are synthesized and characterized by elemental analysis. molar conductivity, magnetic measurement and UV IR spectra. It is found that α_acetylpyridine thiosemicarbazone is tridentate ligand with prridine N, imine N and S as donor atoms. The results of bacteriostatic activity indicate that has high activity aganist Bacillus substills, Staphylococcus and Escherichia Coli.