先天性白血病6例临床特点分析

Analysis of 6 cases of congenital leukemia

目的探讨先天性白血病的临床特点。方法回顾性分析西安市儿童医院新生儿科2005—2008年收治的6例先天性白血病患儿的临床资料。结果母孕期多有特殊有毒有害物质接触史及感染相关病史,先天性白血病的临床表现多种多样,但以皮下结节、贫血、发热、肝脾肿大最为常见,骨髓检查可确诊。结论先天性白血病为少见病,近年有发病增多的趋势,应重视孕期保健、对可疑病例尽早骨髓检查明确诊断。

Objective To investigate the clinical＇ features of congenital leukemia. Methods The clinical data of six cases of congenital leukemia were retrospective analyzed. Results More than a half of these cases had histories of keeping touch with something poisoned or harmful in pregnancy. The clinical manifestation of congenital leukemia could be diversified, but subcutaneous nodules, anemia, fever and hepatosplenomegaly frequently occurred. Bone marrow examination could be helpful for diagnosis. Conclusion Congenital leukemia is a rare disease ; the incidence of this disease has an increasing tendency. We should strengthen antenatal care. Bone marrow should be done in doubtful cases.