危重病患者死亡的早期危险因素研究

The investigation for early risk factors of death sufering from critical care

目的探索入住SICU后死亡的危重病患者早期危险因素。方法按预定的入组标准，选取2005年1月-2006年8月入住SICU的危重病患者作为研究对象。入住后24h内采集相关数据，资料收齐并建立数据库，对30个单因素逐一分析，筛选出8个变量，再进行非条件Logistic回归分析，选出独立因素。结果58例危重病患者，死亡29例，病死率50％；平均动脉压≤70mmHg、动脉血氧分压≤70mmHg及格拉斯哥评分为死亡患者的早期独立危险因素。结论引起危重病患者死亡的因素是多方面的，应采取综合的防治措施才能提高抢救成功率，减少病死率。一旦出现独立危险因素，应及早采取临床措施进行干预。

Objective To explore the early risk factors of death of critical care patients during their stay in SICU. Methods To select the statistics from patients who gathered in SICU from January 2005 to August 2006, according to the pre-fixed standard;collect the relative imformation within 24 hours after they enter SICU and establish the data base ; analyse 30 single factor one by one and eight variables from which obatain the independent factors by using logistic regression model. Results Fatality rate is 50 % （29 out of 58 case died） ;MBP≤70mmHg,PO2≤70mmHg and Glaseow grade were the three independent risk factor of the death.Conclusion The death factors of the crictical care patients are various, therefore we should take integrative measures both preventive and curative to increase the succeed rate. Moreover, we need to take intervention measures once these independent risk factors incurred.