川麦冬皂苷类化学成分的研究

Structural Elucidation of Steroidal Glycosides from Ophiopogon japonicus

从川麦冬[Ophiopogon japonicus(Thunb.)Ker-Gawl.]中分离得到四个皂苷类成分,分别鉴定为14-hydroxy sprengerinin C(1),sprengerinin C(2),ophiogenin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside(3)和β-胡萝卜苷(4,β-sitosterolβ-D-glucopyranoside).其中14-hydroxy sprengerinin C为新的C27甾体皂苷,化合物sprengerinin C为首次从该植物分离得到.运用现代波谱技术,包括二维核磁共振谱和高分辨质谱,对上述化合物的结构进行了确证.

A new steroidal 14-hydroxy sprengerinin C （1） was isolated from the tuber of Ophiopogon ja- ponicus （Thunb.） Ker-Gawl., along with three known compounds, sprengerinin C （2）, ophiogenin-3-O-α-L- rhamnopyranosyl-（1→2）-β-D-glucopyranoside （3） and β-sitosterol-β-D-glucopyranoside （4）. Their structures were established on the basis of IR, HR-MS, 1D and 2D-NMR analyses, as well as by literature comparison of spectroscopic data.