摘要
心肌型脂肪酸结合蛋白(Heart fatty aci-binding protein,H-FABP)是一种低分子量可溶性蛋白,在心肌细胞胞浆中含量丰富,具有组织特异性。心肌损伤后血清中H-FABP水平有时间规律性,其释放至血浆的量与心肌损伤程度成正相关,是一种诊断早期心肌缺血的生化标志物。本文就H-FABP的生理化学特性、在心肌损伤诊断中的应用及法医学的意义作一综述。
Heart fatty-acid-binding protein （H-FABP） is small molecular weight cytosolic protein that is abundant in the heart and has tissue specificity. Concentration of H-FABP changes regulation in serum after the myocardial damage. In addition it has a positive correlation with the degree of myocardial damage. It is an early diagnostic biochemical marker of acute myocardial ischemia. The advance of H-FABP in the research on physioehemieal nature,and its application for myocardial iniury and prospective study of sudden cardiac death in forensic science were reviews.
出处
《医学教育探索》
2008年第8期892-894,共3页
Researches in Medical Education
