青少年心血管危险因素聚集腰围切点的初步探讨

The best waist circumference cut-point for identifying cardiovascular risk factors among adolescents： a preliminary study

目的探讨青少年心血管危险因素聚集的最佳腰围切点。方法秦皇岛地区一项3986名14—18岁青少年的横断面调查。采用受试者工作特征（ROC）曲线分析确定心血管危险因素聚集的最佳腰围切点。结果无论男性还是女性，心血管危险因素聚集的百分比均随着腰围的增加而增加。腰围≥80th百分位点（男性77．0—79．0cm，女性70．0～72．5cm）后心血管危险因素聚集明显升高，年龄标化检出率分别为24．9％（男性）和9．9％（女性）。ROC分析显示以上相应腰围切点具有最佳的敏感性和特异性。结论腰围与心血管危险因素聚集密切相关。预测心血管危险因素聚集的最佳腰围切点被定为80th百分位点。

Objective To explore the best waist circumference （WC） cut-point for identifying cardiovascular risk factors among adolescents. Methods Human basic parameters were measured among 3986 adolescents aged 14 -18 in Qinhuangdao. Receiver operator characteristic curve （ROC） analysis was employed to determine the optimal WC cut-point for detecting cardiovascular risk factors. Results The prevalence of the clustering of cardiovascular risk factors significantly increased after the WC was ≥ 80th percentiles （77.0-79.0 cm for the boys and 70.0 -72.5 cm for the girls）. The age standardization detection rate was 24.9% in boys and 9.9% in girls. ROC analysis showed that the optimal WC cut-point was 80th percentiles, with the sensitivity of 84.3% and specificity of 85.9% in boys, and with sensitivity of 90.7% and specificity of 83.2% in girls. Conclusion There is a significant correlation between WC and cardiovascular risk factors. The optimal WC cut-point for predicting the clustering of cardiovascular risk factors is the 80th percentile.