1Horikawa Y, Oda N, Cox N J, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet, 2000,26 : 163-175.
2Altshuler D, Hirschhorn JN, Klannemark M, et al. The common PPAR gamma Prol2Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet,2000,26: 76-80.
3Gloyn AL,Weedon MN,Owen KR, et al. Large-scale association studies of variants in genes encoding the pancreatic beta cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes,2003,52:568 572.
4Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of tran scription factor 7-like 2 (TCF7L2) gene confers risk of type 2 dia betes. Nat Genet,2006,38: 320 323.
5Sandhu MS,Weedon MN,Fawcett KA,et al. Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet, 2007, 39: 951 -953.
6Gudmundsson J, Sulem P, Steinthorsdottir V, et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet, 2007, 39: 977-983.
7Sladek R, Rocheleau G,Rung J,et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature,2007, 445: 881-885.
8Zeggini E, Weedon MN, Lindgren CM, et al. Replication of ge nome wide association signals in UK samples reveals risk loci for type 2. diabetes. Science,2007,316:1336-1341.
9Scott LJ,Mohlke KL, Bonnycastle LL, et al. A genome-wide as sociation study of type 2 diabetes in Finns detects multiple susceptibility variants. Science, 2007,316 : 1341-1345.
10Diabetes Genetics Initiative of Broad Institute of Harvard and MIT,Lund University,and Novartis Institutes of BioMedical Research,Saxena R,Voight BF, Lyssenko V,et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyeeride levels. Science,2007,316: 1331-1336.
同被引文献36
1Wei FY,Tomizawa K.CDK5:a potential herapeutic target for the treatment of neurodegenerative diseases and diabetes mellitus[J].Mini Rev Med Chem,2007,7 (10):1070-1074.
3Sanghera DK,Ortega L,Hab S,et al.Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs:PPARG2 (Pro12Ala),IGF2BP2,TCF7L2 and FTO variants confer a significant risk[J].BMC Med Genet,2008,9:59.
4Wang X,Ching YP,Lam WH,et al.Identification of common protein association region in neuronal Cdk5 activator[J].J Biol Chen,2000,13:31763-31769.
5Ching YP,Qi Z,Wang JH,et al.Cloning of three novel neuronal Cdk5 activator binding proteins[J].Gene,2000,25:285-294.
6Zeggini E,Weedon MN,lingren CM,et al.Relication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes[J].Science,2007,316:1336-1341.
7Arao M,Murase K,Kusakabe A,et al.Prevalence of diabetes mellitus in Japanese patients infected chronically with hepatitis C virus[J].J Gastroenterol,2003,38:355-360.
8Koike K.Hepatitis C as a metabolic disease:Implication for the pathogenesis of NASH[J].Hepatol Res,2005,33:145-150.
9Ling C,Groop L.Epigenetics:a molecular link between environmental factors and type 2 diabetes.Diabetes,2009,58:2718-2725.
10Zeggini E,Scott LJ,Saxena R,et al.Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.Nat Genet,2008,40:638-645.