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瑞芬太尼复合异丙酚静脉麻醉在肝癌I^(125)粒子植入术中的应用 被引量:1

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摘要 目的:探讨瑞芬太尼复合异丙酚静脉麻醉在肝癌I125粒子植入术中应用是否安全、有效。方法:选择拟行I125粒子植入术的肝癌患者50例,随机分为瑞芬太尼复合异丙酚(R组)组与芬太尼复合异丙酚(F组)组,每组各25例。R组静脉滴注瑞芬太尼1μg·kg-1,再用微量泵输注瑞芬太尼0.1μg·kg-1·min-1,F组单次静脉滴注芬太尼1.5μg·kg-1。两组均以异丙酚微量泵注1~2μg·kg-1·min-1维持麻醉。观察并记录患者术前、手术开始时、手术开始后10min及术后苏醒时的平均动脉压、心率、脉搏氧饱和度及呼吸频率。记录术中体动、呼吸暂停的次数。结果:R组患者的清醒时间(6.5±1.8)min显著短于F组(12.7±2.4)min;术中R组的平均动脉压下降明显低于F组(P<0.05);术中体动R组(5例)少于F组(11例),呼吸暂停R组(12例)多于F组(6例)。结论:瑞芬太尼复合异丙酚静脉麻醉在肝癌I125粒子植入术中应用效果确切、安全,但必须加强循环呼吸监测。
作者 周辉
出处 《现代医药卫生》 2008年第19期2900-2901,共2页 Journal of Modern Medicine & Health
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参考文献4

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