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雌孕激素对子宫内膜上皮细胞调控作用的分子机制

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摘要 雌、孕激素主要由卵巢周期性分泌，它们对子宫的结构与功能起着重要的调节作用，其对子宫内膜上皮细胞的作用表现为：雌激素促进子宫内膜上皮细胞的增殖，孕激素抑制上皮细胞增殖，促使其分化为具有分泌功能的上皮，迎接胚胎着床。由于细胞的增殖、分化与细胞周期进程密切相关，而细胞周期的进程受到多种细胞周期调控蛋白的调控， 显然，子宫内膜所发生的周期性变化与雌激素、孕激素对这些蛋白的作用密切相关。本文就雌、孕激素通过影响细胞周期调控蛋白进而对子宫内膜细胞增殖、分化调控作用的分子机制作一简单综述。
作者 白玛康卓 岳利民
机构地区 西藏大学医学院 四川大学华西基础医学与法医学院生理教研室
出处 《现代医药卫生》 2008年第19期2919-2921,共3页 Journal of Modern Medicine & Health
关键词 子宫内膜上皮细胞 雌孕激素 调控作用 分子机制 细胞周期调控蛋白 上皮细胞增殖 细胞周期进程 周期性变化
分类号 R339.22 [医药卫生—人体生理学] R169.41 [医药卫生—公共卫生与预防医学]
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参考文献15

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二级参考文献19

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现代医药卫生
2008年 第19期

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