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198株黏液罗氏菌的临床分离情况及耐药性分析 被引量:1

Analysis of isolated ratio and drug resistance of 198 strains of Rothia mucilaginosus from clinical specimens
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摘要 目的对黏液罗氏菌的分离率进行统计,并对其耐药性进行分析。方法用常规方法对临床分离的198株黏液罗氏菌进行鉴定。药敏试验采用纸片扩散法,并用E-test药敏条作对照。结果黏液罗氏菌的临床分离率为13%,临床可选择的药物为头孢曲松、利福平、四环素、万古霉素,本菌对环丙沙星、苯唑西林、复方磺胺甲口恶唑均高度耐药。结论对于经常使用抗菌药物、免疫力低下及长期住院的危重患者,黏液罗氏菌是一种重要的机会致病菌,由于耐药菌株的不断出现,建议临床根据药敏试验结果选用抗菌药物。 Objective To make statistics of the isolated ratio and analyze the drug resistance of Rothia mucilaginosus. Methods 198 strains of Rothia mucilaginosus were identified with routine method. Drug resistance was analyzed by the disk diffusion method with the E-test method as control. Results The isolated ratio of Rothia mucilaginosus was 13%. The Rothia mucilaginosus were sensitive to ceftriaxone, rifadin, tetracycline, vaneomycin and highly resistant to ciprofloxacin, oxacillin and sulfamethoxazole. Conclusions Rothia rnucilaginosus is an important opportunistic pathogen for the long-term hospitalized patient usually used antibiotincs and with hypoimmunity. It is important to select antibiotics based on the results of the drug sensitivity of the pathogens, because the occurrence of the drug resistant strains increases.
出处 《检验医学》 CAS 北大核心 2008年第5期494-496,共3页 Laboratory Medicine
关键词 黏液罗氏菌 分离率 耐药性 Rothia mucilaginosus Identification Drug resistance
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参考文献6

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二级参考文献18

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共引文献9

同被引文献11

  • 1金艳,张春和,马金群,陈东科.黏液罗氏菌的分离和鉴定方法及临床意义分析[J].中华检验医学杂志,2007,30(2):231-232. 被引量:5
  • 2Collins MD,Hutson RA,Baverud V. Characterization of a Rothia-like organism from a mouse:description of Rothia nasimurium sp.nov.and reclassification of Stomatococcus mucilaginosus as Rothia mucilaginosa comb.nov[J].International Journal of Systematic and Evolutionary Microbiology,2000,(03):1247-1251.
  • 3李仲兴;赵建宏;杨敬芳.革兰阳性球菌与临床感染[M]北京:科学出版社,2007435-445.
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  • 6Pérez-Vega C,Narváez J,Calvo G. Cerebral mycotic aneurysm complicating Stomatococcus mucilaginosus infective endocarditis[J].Scandinavian Journal of Infectious Diseases,2002,(11):863-866.
  • 7Bureau-Chalot F,Piednoir E,Bazin A. Postoperative spondylodiskitis due to Stomatococcus mucilaginosus in an immunocompetent patient[J].Scandinavian Journal of Infectious Diseases,2003,(02):146-147.
  • 8Gruson D,Hilbert G,Pigneux A. Severe infection caused by Stomatococcus mucilaginosus in a neutropenic patient:case report and review of the literature[J].Hematology and Cell Therapy,1998,(04):167-169.
  • 9McWhinney PH,Kibbler CC,Gillespie SH. Stomatococcus mucilaginosus:an emerging pathogen in neutropenic patients[J].Clinical Infectious Diseases,1992,(03):641-646.
  • 10Fanourgiakis P,Georgala A,Vekemans M. Bacteremia due to Stomatococcus mucilaginosus in neutropenic patients in the setting of a cancer institute[J].Clinical Microbiology and Infection,2003,(10):1068-1072.doi:10.1046/j.1469-0691.2003.00772.x.

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