摘要
生理状态下，神经系统与免疫系统主要通过下丘脑-垂体-肾上腺轴、交感神经系统和副交感神经系统（迷走胆碱能通路）维持机体内稳态。卒中后，机体内稳态失衡导致外周免疫抑制，称为卒中诱导的免疫抑制综合征，其机制仍在研究之中。文章从上述3条通路出发，对卒中诱导外周免疫抑制的机制和临床意义进行了综述。
The nervous system and the immune system maintain homeostasis mainly through the hypothalamo-pituitary-adrenal （HPA） axis, the sympathetic nervous system and the parasympathetic nervous system （vagal cholinergic pathway）, The homeostasis is broken after stroke, and results in peripheral immunosuppression, wfiich is called stroke-induced immunodepression syndrome. Its mechanism is still under investigation.The article reviews the mechanism and clinical significance of stroke-induced peripheral immunodepression through the above three mentioned pathways.
出处
《国际脑血管病杂志》
2008年第8期620-624,共5页
International Journal of Cerebrovascular Diseases
关键词
卒中
免疫抑制
机制
stroke
immunodepression
mechanism
