腹内压对急性胰腺炎的临床意义

The clinical correlation between the severity of acute pancreatitis and intra- abdominal pressure

目的研究急性胰腺炎的病变严重程度与腹内压的关系。方法对发病48h内住院治疗的45例急性胰腺炎患者，在入院后每隔8h采用间接法测量腹内压，如病情有所缓解（肛门排气）或需手术治疗，则停止测压。并收集Ranson指标及Apache Ⅱ评分指标。结果腹内压与Ranson指标存在一定的相关，相关系数r=0．735（P〈0．05），决定系数r^2=0．568。腹内压与Apache Ⅱ评分存在良好的相关，相关系数r=0．874（P〈0．01），决定系数r2=0．763。结论腹内压的变化与急性胰腺炎的病变严重程度存在相关性。

Objective To investigate the correlation between the severity of acute pancreatitis and intra- abdominal pressure. Methods Forty - five patients with acute pancreatitis admitted in hospital within 48 hours from the disease onset were recruited.The intra - abdominal pressure of all the patients was measured q8h by indirect method after admission.The procedure would be terminated when either there were manifestations of disease subside（e.g.passing flatus）or disease progress that surgical intervention was needed. The Ranson＇ s criteria and APACHE Ⅱ score were also recorded. Results Intra- abdominal pressure also correlated with Ranson＇ s criteria（ r = 0.735, P 〈 0.05, r^2 = 0.568）. Significant correlation was demonstrated between Intra - abdominal pressure and APACHE Ⅱ score （ r = 0.874, P 〈 0.01, r2 = 0.763）. Conclusion Change of the intra - abdominal pressure correlates with the severity of acute panereatitis.