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螺内酯对急性心肌梗死后发生心力衰竭的影响

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摘要 目的:探讨螺内酯对急性心肌梗死(AMI)后心力衰竭发生和患者生存的影响.方法:将武汉市第八医院近3年中收治的AMI 55例列入本研究,28例在常规治疗基础上加螺内酯25mg bid为治疗组,另27例只用常规治疗为对照组,治疗30d.第1~10 d,第11~20 d,第21~30 d分别统计3个时段内发生心力衰竭及其恶化死亡情况.结果:第1~10 d时间段内发生心衰及死亡例数差异无统计学意义(P>0.05),后两个时间段内治疗组发生心衰及死亡例数明显低于对照组(P<0.05).在30d治疗期间中治疗组与对照组疗效相比差异有统计学意义(P<0.05),结论:在AMI后早期应用螺内酯可降低心衰发生率及其死亡率.
作者 柴燕
出处 《江汉大学学报(自然科学版)》 2008年第3期79-80,共2页 Journal of Jianghan University:Natural Science Edition
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