摘要
目的探讨脑梗死患者脂蛋白(a)[Lp(a)]水平的变化及意义。方法对120例脑梗死患者和80例健康体检者,采用胶乳增强免疫透射比浊法测定Lp(a)含量。结果脑梗死组Lp(a)含量的中位数为326.0 mg/L,健康对照组为128.5 mg/L,脑梗死组明显高于健康对照组,差异有统计学意义(t=3.624,P<0.01)。脑梗死患者Lp(a)异常率(28.3%)明显高于健康对照组(7.5%),差异有统计学意义(χ2=13.02,P<0.01)。结论脑梗死患者Lp(а)水平明显升高,是脑梗死发病的重要危险因素。
Objective To investigate the change of serum lipoprotein （a）[Lp （a）]in patients with cerebral infarction and its clinical significance. Methods Latex-enhanced immunoturbidimetry was applied to determining serum level of Lp （a） in 120 paitents with cerebral infarction （cerebral infarction group） and 80 healthy subjects （healthy control group）. Results The median value （mg/L） and abnormality rate of Lp （a） in cerebral infarction group were significantly higher than those in healthy control group （326.0 vs 128.5 ,t=3. 624,P〈0.01 ;28.3% vs 7.5%, χ^2=13.02,P〈0.01, respectively）. Conclusion Significantly elevated serum Lp （a） level is a vital risk factor for onset of cerebral infarction.
出处
《检验医学与临床》
CAS
2008年第19期1159-1160,共2页
Laboratory Medicine and Clinic
关键词
脑梗死
脂蛋白(a)
危险因素
cerebral infartion
lipoprotein （a）
risk factors
