期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

过敏性紫癜相关基因多态性研究进展

Progress of gene polymorphism in Henoch-Schonlein purpura
原文传递
导出
摘要 许多研究显示，疾病的发生、发展以及治疗效果与基因的多态性有关。近年来一些研究结果显示，某些基因多态性与过敏性紫癜及过敏性紫癜肾炎的发病机制、易感性、病理进展及预后明显相关，如肾素一血管紧张素系统基因、人类白细胞抗原基因、细胞因子基因、PAX2基因、一氧化氮合酶基因等。该文就过敏性紫癜相关基因多态性的研究进展作一综述。
作者 陈静(综述) 易著文(审校)
机构地区 中南大学湘雅三医院皮肤科 中南大学湘雅二医院小儿肾病研究所
出处 《国际儿科学杂志》 2008年第5期444-447,共4页 International Journal of Pediatrics
关键词 紫癜 过敏性 肾炎 多态现象 遗传
分类号 R726.923.4 [医药卫生—儿科] R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献34

  • 1Yoshioka T,Xu YX,Yoshida H,et al.Deletion polymotphism of the angiotensin converting enzyme gene predicts persistent proteinuria in Henoch-Schonlein purpura nephritis. Arch Dis Child, 1998,79(5) :394-399.
  • 2周建华,田雪飞,徐钦儒.Angiotensin-converting Enzyme Gene Insertion/Deletion Polymorphism in Children with Henoch-Schonlein Purpua Nephritis[J].Journal of Huazhong University of Science and Technology(Medical Sciences),2004,24(2):158-161. 被引量：17
  • 3Amoroso A, Danek G, Vatta S, et al. Polymorphisms in angiotensin-converting enzyme gene and severity of renal disease in Henoch-Schoenlein patients. Nephrol Dial Transplant, 1998, 13(12) :3184-3188.
  • 4Dudley J, Afifi E, Gardner A, et al. Polymorphism of the ACE gene in Henoch-Schonlein purpura nephritis. Pediatr Nephrol,2000,14(3) :218-220.
  • 5Brodkiewicz A, Ciechanowicz A, Urbanska A, et al. The I/D polymorphism of the ACE gene in children with Henoch-Schoenlein purpura. Pol Merkuriusz Lek,2000,8(46) :236-238.
  • 6Ozkaya O, Soylemezoglu O, Gonen S, et al. Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement. Clin Rheumatol, 2006,25 (6) : 861-865.
  • 7Amoli MM,Thomson W, Hajeer AH,et al.HLA-B35 association with nephritisin Henoch-Schonlein purpura. J Rheumatol, 2002,29 (5) : 948-949.
  • 8任少敏,仝林虎,锡林高娃,睢俊卿,高忠献,闫文瑛,李维才.内蒙古汉族儿童过敏性紫癜与HLA-DQA1基因的关联性研究[J].中华医学遗传学杂志,2002,19(1):58-60. 被引量：14
  • 9Amoli MM, Thomson W, Hajee: AH, et al. HLA-DRB1 * 01 association with Henoch-Schonlein purpurain patients from northwest Spain. Rheumatology, 2001,28(6) : 1266-1270.
  • 10任少敏,杨光路,仝林虎,寿琼华,李维才.蒙古族儿童过敏性紫癜及其器官损害与HLA-DRB1等位基因的关联性[J].中国基层医药,2005,12(12):1659-1661. 被引量：3

二级参考文献23

  • 1熊平,扬颖,龚非力.一种新的HLA─Ⅱ类基因分型方法——PCR／SSP技术的建立[J].免疫学杂志,1996,12(4):258-261. 被引量：41
  • 2[1]Sumiya M, Super M, Tabona P, Levinsky R J, Arai T, Turner MW, et al. Molecular basis of opsonic defect in immunodeficient children [J]. Lancet, 1991, 337(8757): 1569- 1570.
  • 3[2]Lipscombe RJ, Sumiya M, Hill AV, Lau YL, Levinsky RJ, Summerfield JA, et al. High frequencies in African and non African populations of independent mutations in the mannose binding protein gene [J]. Hum Mol Genet, 1992, 1(9): 709- 715.
  • 4[3]Madsen HO, Garred P, Kurtzhals JAL, Lamm LU, Ryder LP, Thiel S, et al. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein[J]. Immunogenetics, 1994, 40(1): 37- 44.
  • 5[4]Mills JA, Michel BA, Bloch DA, Calabrese LH, Hunder GG, Arend WP, et al. The American College of Rheumatology 1990 criteria for the classification of Henoch-Schonlein purpura [J]. Arthritis Rheum, 1990, 33(8): 1114-1121.
  • 6[5]Lau YL, Lau CS, Chan SY, Karlbery J, Turner MW. Mannose binding protein in chinese patients with systemic lupus erythematosus [J]. Athritis Rheum, 1996, 39(4): 706-708.
  • 7[6]GarredP, ThielS, MadsenHO, Ryder LP, JenseinusJC, Svej gaard A. Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentration [J]. Clin Exp Immunol, 1992, 90(3): 517 - 521.
  • 8[7]Endo M, Ohi H, Ohasawa I, Fujita T, Matsushita M. Comple ment activation through the lectin pathway in patients with Henoch-Schonlein purpura nephritis [J]. Am J kidney Dis, 2000, 35(3): 401-407.
  • 9[8]Kurata H, Sannoh T, Kozntsumi Y, Yokota Y, Kawasaki T. Structure and function of mannan-binding proteins isolated from human liver and serum [J]. J Biochem, 1994, 115(6): 1148- 1154.
  • 10[9]Matsushita M. The lectin pathway of the complement system[J]. Microbiol Immunol, 1996, 40(12): 887-893.

共引文献42

国际儿科学杂志
2008年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部