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以泰索帝为主联合化疗治疗51例晚期妇科恶性肿瘤

Taxotere Based Combination Chemotherapy for 51 Cases with Advanced Gynecologic Cancer
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摘要 [目的]观察以泰索帝为主的联合化疗治疗晚期妇科恶性肿瘤的疗效。[方法]泰索帝组51例晚期妇科恶性肿瘤患者,采用方案为泰索帝75mg/m2+顺铂60mg/m2+环磷酰胺600mg/m2。对照组为同期60例中晚期妇科恶性肿瘤患者,方案采用PAC(顺铂+环磷酰胺+表阿霉素)及VBP方案(长春新碱+平阳霉素+顺铂)。均化疗2 ̄6个周期。[结果]泰索帝组与对照组中位生存期分别为8.5个月和4个月(P<0.01),有效率(CR+PR)分别为43.1%与19.8%(P<0.05)。化疗毒副反应主要是骨髓抑制与脱发。[结论]以泰索帝为主的联合化疗治疗晚期妇科恶性肿瘤尤其是卵巢癌及输卵管癌近期疗效好,毒副反应较轻。
机构地区 黑龙江省医院
出处 《肿瘤学杂志》 CAS 2008年第9期758-759,共2页 Journal of Chinese Oncology
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