胰腺癌的遗传易感性

Genetic susceptibility of pancreatic carcinoma

胰腺癌是一种致死性疾病,即使行胰腺癌的彻底根治术,其5年存活率仍不足5%。胰腺癌的发病及转移与其他肿瘤一样,是由遗传性和获得性肿瘤生成基因累积所致,而单纯由遗传因素引起的肿瘤对研究肿瘤的发生机制具有独特意义。近年来,基因遗传因素与肿瘤发生的关系逐渐引起肿瘤研究人员的重视,重新调整肿瘤预防策略。

Pancreatic carcinoma is a kind of fatal disease. The five-year survival rate of pancreatic carcinoma can＇ t reach five persent, which had radical operation. As other kinds of carcinoma, the pathogenesis and metastasis of pancreatic carcinoma result from the genic accumulation of the hereditary and acquired oncogenesis, while the carcinoma that only coming from heredity has special meaning for the tumorigenic research. The relationship of genie inheritance and tumorigenesis has recently drawn the researchers＇ attention and made them readjust the preventive strategies of carcinoma.