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家族性ALS发病机制中SOD1突变体作用的研究进展 被引量:1

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作者 刘骅 蒋伟
出处 《重庆医学》 CAS CSCD 2008年第18期2116-2118,共3页 Chongqing medicine
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参考文献20

  • 1Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis[J]. Nature, 1993,362 (6415) :59.
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  • 4Grieb P. Transgenic models of amyotrophic lateral sclerosis[J]. Folia Neuropathol, 2004,42 (4) : 239.
  • 5SubramaniamJR, Lyons WE, Liu J,et al. Mutant SOD1 causes motor neuron disease independent of copper chaperon-mediated copper loading[J]. Nat Neurosci, 2002,5 (4):301.
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  • 9Zimmerman MC, Oberley LW, Flanagan SW. Mutant SOD1 induced neuronal toxicity is mediated by increased mitochondrial superoxide levels[J]. J Neurochem, 2007, 102(3) :609.
  • 10Tiwari A, Xu Z, Hayward LJ. Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis[J]. J Biol Chem, 2006,280(33) : 29771.

二级参考文献18

  • 1[1]Walker MP, Schlaberg R, Hays AP. Absence of echovirus sequences in brain and spinal cord of amyotrophic lateral sclerosis patients[J]. Ann Neurol, 2001, 49(2):249.
  • 2[2]Rosen DR, Siddique T, Patterson D, et al. Mutations in Cu/Zn superoxide dismutase gene are associated with famalial amyotrophic lateral sclerosis[J]. Nature, 1993, 362(1):59.
  • 3[3]Gurney ME, Fleck TJ, Himes CS, et al. Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis[J]. Neurology, 1998, 50(1):62.
  • 4[4]Ince PG, Tomkins J, Slade JY, et al. Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu/Zn superoxide dismutase: molecule pathology of five cases of ALS[J]. J Neuropathol Exp Neurol, 1998, 57(3):895.
  • 5[5]Weber M, Eisen A, Stewart HG, et al. Preserved slow conducting corticomotoneuronal projections in amyotrophic lateral sclerosis with autosomal recessive D90A Cu Zn-superoxide dismutase mutation[J]. Brain, 2000, 123 ( 7):1505.
  • 6[6]Cafe C, Testa MP, Sheldon PJ, et al. Loss of oxidation-reduction specificity in amyotrophic lateral sclerosis-associated CuZnSOD mutants[J]. J Mol Neurosci, 2000, 15(2):71.
  • 7[7]Cleveland DW. From Charcot to SOD1: mechanisms of selective motor neuron death in ALS[J]. Neuron, 1999, 24(3):515.
  • 8[8]Pasinelli P, Houseweart MK, Brown RH , et al. Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis[J]. Proc Natl Acad Sci USA, 2000, 97(25): 13901.
  • 9[9]Li M, Ona VO, Guegan C, et al. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model[J]. Science, 2000, 288(5464):335.
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同被引文献6

  • 1黄慧,张成.家族性ALS的SOD1基因突变及发病机制研究进展[J].国外医学(神经病学.神经外科学分册),2004,31(6):511-514. 被引量:5
  • 2Siun CT,Beow CY.DNA RNA and Protein Extraction:The Past and The Present[J].Journal of Biomedicine and Biotechnology,2009,11:1-10.
  • 3Vlug AS,Jaarsma D.Long term proteasome inhibition does not preferentially afflict motor neurons in organotypical spinal cordeultures[J].Amyotroph Lateral Scler Other Motor Neuron Disord,2004,5(1):16-21.
  • 4Shaw BF,Valentine JS.How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein[J].Trends Biochem Sci,2007,32(2):78.
  • 5丘创华,周勇军,侯敢,黄迪南.肌萎缩性侧索硬化症相关的Cu,Zn-SOD[J].中国生物化学与分子生物学报,2008,24(2):107-112. 被引量:3
  • 6王贵民,孟伟,谭毓铨.肝细胞制备和培养技术[J].吉林医学,2003,24(1):11-12. 被引量:3

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