良性前列腺增生并发急性尿潴留相关因素分析

The relevant factors associated with the acute urinary retention complicating benign prostatic hyperplasia

目的探讨良性前列腺增生(BPH)并发急性尿潴留(AUR)的相关因素。方法回顾性分析112例BPH患者的相关资料。其中曾发生AUR的患者43例(A组),无AUR的患者69例(B组)。比较2组间患者的年龄、国际前列腺症状评分(IPSS)、最大尿流率(Qmax)、前列腺特异性抗原(PSA)、前列腺总体积(PV)、前列腺移行区体积(TZV)、移行区指数(TZI)及术后病理前列腺炎症程度分级、增生类型、前列腺梗死发生率,并进行统计学处理。结果A组患者PSA、TZV、TZI均较B组升高(P<0.01)。A组前列腺炎症程度分级明显高于B组(P<0.01)。A组患者腺上皮增生为主所占比例明显高于B组(P<0.05)。2组间年龄、IPSS、PV、Qmax、前列腺梗死发生率差异均无统计学意义(P>0.05)。结论PSA水平、TZV、TZI可作为预测BPH并发AUR的良好指标;前列腺炎症程度、前列腺组织中腺上皮细胞比率增高可能是AUR的危险因子。

Objective To investigate the relevant factors associated with the complicating acute urinary retention （AUR） of benign prostatic hyperplasia （BPH）. Methods A retrospective study was made on 112 BPH patients divided into an AUR group A （n = 43） and a non -AUR group B （n = 69）. Comparisons covered the patients＇ age, international prostate symptom score （IPSS）, peak urinary flow rate （Qmax）, prostate volume （PV）, transition zone volume （TZV）, transition zone index （TZI）, prostate- specific antigen （PSA）, pathologic grade of prostatitis, type of hyperplasia and occurrence of prostate infarction. Results The TZV, TZI and PSA were significantly higher in group A than in group B （ P 〈 0.01 ）. The pathologic grade of prostatitis and the type of hyperplasia were more advanced in group A. No significant differences in age, IPSS, PV, Qmax and occurrence of prostate infarction were found in between. Conclusion TZV, TZI, PSA are the factors predicting the occurrence of AUR in BPH patients; the higher pathologic grade of prostatitis and higher percentage of epithelial cells in prostate may be the risk factors for AUR.