秦皇岛市16-18岁青少年血三酰甘油检测结果分析

Analysis of Serum Triglyceride and Risk Factors in Adolescents Aged 16-18 in Qinhuangdao City

目的了解秦皇岛市16-18岁青少年血三酰甘油水平,分析高三酰甘油的危险因素,为儿童青少年代谢综合征的早期预防提供依据。方法通过分层整群随机抽样,测定秦皇岛市2 395名16-18岁青少年身高、体重、腰围、血压、空腹血糖、血三酰甘油（TG）和高密度脂蛋白胆固醇（HDL-C）水平。结果血三酰甘油的分布P95为1.75 mmol/L。高三酰甘油血症的检出率为5.8%,男、女生高三酰甘油血症检出率分别为6.9%和4.7%,差异有统计学意义（χ2=5.160,P〈0.05）。对血三酰甘油的影响因素进行多元线性回归分析显示,男生组最佳模型引入HDL-C（β=-0.511,P〈0.01）和腰围（β=0.009,P〈0.01）,女生组最佳模型引入HDL-C（β=-0.426,P〈0.01）和腰围身高比（β=1.77,P〈0.01）。结论青少年高三酰甘油血症患病率较高,中心性肥胖和低高密度脂蛋白胆固醇是引发青少年高三酰甘油血症的主要危险因素。

Objective To investigate the current situation of serum triglyceride,to analyze its risk factors in adolescents aged 16-18 years and to provide evidence for the early prevention against metabolism syndrome.Methods A cross-sectional survey was conducted among 2 395 adolescents aged 16-18 years.Measurements included height,weight,waist circumference,blood pressure,fasting plasma glucose（FPG）,serum triglyceride（TG） and high-density lipoprotein cholesterol（HDL-C）.Results The 95th percentile for TG was 1.75 mmolL.The positive rate of hypertriglyceridemia was 5.8%.The positive rate of boys and girls was 6.9% and 4.7% respectively（χ2=5.160,P〈0.05）.Multiple linear regression analysis showed that the risk factors of serum triglyceride of boys were HDL-C（β=-0.511,P〈0.01）and waist circumference（β=0.009,P〈0.01）,the factors of girls were HDL-C（β=-0.426,P〈0.01） and waistheight ratio（β=1.77,P〈0.01）.Conclusion The positive rate of hypertriglyceridemia is high in adolescents.Central obesity and low HDL-C are the main risk factors to adolescent hypertriglyceridemia.