医齿科用海洋生物粘结剂的研究进展

Achievement in Research Work on Marine Bio-adhesive in Odontology

目的:介绍未来医齿科用海洋生物粘结剂的研究状况。方法:通过提出医齿科用粘结剂的要求与目前存在的缺陷,介绍海洋生物粘结剂的优点;重点描述了贻贝海洋生物粘结蛋白(BP)的基础研究及其应用研究前景,对其主要成分及作用进行综述。结果:应用基因重组技术是目前制备BP最有效、经济的方法,可以解决天然胶难保存、获取量小的缺点,为未来生物粘结剂的制备奠定技术基础。结论:基因重组技术制备的海洋生物粘结剂,不久将有可能应用于医学与牙科临床。

Objective To introduce the achievement in the research work of marine bio-adhesive used in medical fields in future. Methods The merits of marine bio-adhesive was elucidated and the requisition and remained defects of medical and dental adhesives were analyzed. The applicable prospects of mussel bio-adhesive were highlighted particularly on the components and functions. Results At present, gene reconstruction technique is the most useful and economic way to produce bio-adhesive protein from marine biomaterial. By that method, the problems of storage difficulty and resource limitation can be solved. Conolusion The marine bio-adhesive produced by gene reconstruction will he used in medical and dental treatment in the future.